Abstract
Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual partner. Once infected, an individual has to live with HSV for their entire life, and HSV infection can lead to meningitis, encephalitis, and neonatal herpes as a result of vertical transmission. In addition, HSV infection increases the rates of human immunodeficiency virus (HIV) infection and transmission. Because of the high burden of genital herpes, HSV vaccines have been developed, but none have been very successful. In this review, we discuss the current status of genital herpes vaccine development.
| Original language | English |
|---|---|
| Article number | 420 |
| Pages (from-to) | 1-13 |
| Number of pages | 13 |
| Journal | Vaccines |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 2020 |
Keywords
- Genital herpes
- Herpes simplex virus
- HSV
- Vaccine
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Kim, H. C. (2020). Vaccines against genital herpes: Where are we? Vaccines, 8(3), 1-13. Article 420. https://doi.org/10.3390/vaccines8030420
Kim, Hyeon Cheol ; Lee, Heung Kyu. / Vaccines against genital herpes : Where are we?. In: Vaccines. 2020 ; Vol. 8, No. 3. pp. 1-13.
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title = "Vaccines against genital herpes: Where are we?",
abstract = "Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual partner. Once infected, an individual has to live with HSV for their entire life, and HSV infection can lead to meningitis, encephalitis, and neonatal herpes as a result of vertical transmission. In addition, HSV infection increases the rates of human immunodeficiency virus (HIV) infection and transmission. Because of the high burden of genital herpes, HSV vaccines have been developed, but none have been very successful. In this review, we discuss the current status of genital herpes vaccine development.",
keywords = "Genital herpes, Herpes simplex virus, HSV, Vaccine",
author = "Kim, {Hyeon Cheol} and Lee, {Heung Kyu}",
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year = "2020",
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doi = "10.3390/vaccines8030420",
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Kim, HC 2020, 'Vaccines against genital herpes: Where are we?', Vaccines, vol. 8, no. 3, 420, pp. 1-13. https://doi.org/10.3390/vaccines8030420
Vaccines against genital herpes: Where are we? / Kim, Hyeon Cheol; Lee, Heung Kyu.
In: Vaccines, Vol. 8, No. 3, 420, 09.2020, p. 1-13.
Research output: Contribution to journal › Review article › peer-review
TY - JOUR
T1 - Vaccines against genital herpes
T2 - Where are we?
AU - Kim, Hyeon Cheol
AU - Lee, Heung Kyu
N1 - Publisher Copyright:© 2020 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2020/9
Y1 - 2020/9
N2 - Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual partner. Once infected, an individual has to live with HSV for their entire life, and HSV infection can lead to meningitis, encephalitis, and neonatal herpes as a result of vertical transmission. In addition, HSV infection increases the rates of human immunodeficiency virus (HIV) infection and transmission. Because of the high burden of genital herpes, HSV vaccines have been developed, but none have been very successful. In this review, we discuss the current status of genital herpes vaccine development.
AB - Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual partner. Once infected, an individual has to live with HSV for their entire life, and HSV infection can lead to meningitis, encephalitis, and neonatal herpes as a result of vertical transmission. In addition, HSV infection increases the rates of human immunodeficiency virus (HIV) infection and transmission. Because of the high burden of genital herpes, HSV vaccines have been developed, but none have been very successful. In this review, we discuss the current status of genital herpes vaccine development.
KW - Genital herpes
KW - Herpes simplex virus
KW - HSV
KW - Vaccine
UR - http://www.scopus.com/inward/record.url?scp=85089113387&partnerID=8YFLogxK
U2 - 10.3390/vaccines8030420
DO - 10.3390/vaccines8030420
M3 - Review article
AN - SCOPUS:85089113387
SN - 2076-393X
VL - 8
SP - 1
EP - 13
JO - Vaccines
JF - Vaccines
IS - 3
M1 - 420
ER -
Kim HC, Lee HK. Vaccines against genital herpes: Where are we? Vaccines. 2020 Sep;8(3):1-13. 420. doi: 10.3390/vaccines8030420
